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Anti-HCV-positive patients with primary liver cancer LAK activity, IL-2 and sIL-2R levels observed

. 2R levels were positively correlated, r value of 0.471 and 0.54, P 0.05. Discussion of hepatitis C virus can be} I drive from the host organism immune regulation abnormalities. IL. 2, LAK activity and by enhancing the induction of IL. 2R expression plays an important immune regulatory ashamed to use. I found work in recent years, from the cell membrane |, 2R off the formation of slL. 2R, the body of HBv infection have immune activation,[link widoczny dla zalogowanych], there are reports of immunosuppression. anti-HCV-positive and 30 anti-HCV-negative PHC patients down PBMC and LAK activity,[link widoczny dla zalogowanych], IL.2 detected levels and serum anti Hcv slL2R negative, positive PHC patients and IL.2 of LAK Tim were significantly lower than normal. And slL .2 R levels were significantly higher for normal subjects: PHC compared to patients with HCV-negative, anti-HCV-positive patients IIr2 PHC and LAK activity levels decline. slL.2R levels, but the difference was not significant: at the same time. IL2 and sIL.2R increase was positively correlated with abnormal ALT. and LAK activity was not significantly correlated ALJT exception. Tip in the PHC patients. HCV infection,[link widoczny dla zalogowanych], possibly through activation of Tc cells while in line at the same time cause liver injury HCv cell damage,[link widoczny dla zalogowanych], ChinJDigAprilI. 96.v0i16 . No2 compete with IL.2 to IL.2 reduced. resulting in decreased LAK-tim. This IL.2 and LAK cells, anti-virus and anti-tumor effect could be weakened. so HCv or HCv infection and growth of cancer cells to survive . that HCV infection on immune function may play a dual positive and negative immune regulation. so. OF believes that the PHC patients, signs in the detection of anti-HCV, but also should be monitored sIL.2R change, not only help to understand the patient's immune status of PHC. and help guide treatment of the patient's station manager. but. from our fight against HCV negative, positive PHC patients in the LAK activity of PBMC, IL.2 and slL 2R level is not a statistically significant differences in results also can be seen, HCV patients on immune function of PHC is not the only factors that may have other factors burning involved. that the patient's immune PHC pathogenic mechanism is extremely complex. other factors and also the relationship between immune response be further explored.
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