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Guess, what is the dead on human history's most acute contagion? Smallpox, the plague? Not be,[link widoczny dla zalogowanych] ,, it is the grippe that everybody has gotten. In 1918 ～ between 1919, a flu sweeps across the whole world, estimate at that time whole world the population of 1/3 (about 500 million person) by infection, dead number estimates person of at least 2 ten million conservatively, estimation is as high as somebody 100 million people, actual dead number may be controlled in person of 5 ten million.
Of course,[link widoczny dla zalogowanych] ,, flu can appear every year popular, although unlike 1918 ～ 1919 that time so miserable intense, but estimate according to World Health Organization, the whole world has the person of 15 ％ of 5 ～ every year to be affected, 5 million person of 300 ～ be in a bad way, 500 thousand person of 25 ～ dies. Every other still can erupt for some time the flu craze with infectivity and particularly strong noxiousness, in last centuries besides 1918 ～ 1919 that, still had appeared twice: 1957 ～ 58 years the flu between makes about 1 million person dies, 69 years the flu craze between brings about 1968 ～ about 750 thousand person dies. Pardonable flu became the contagion that is studied most except AIDS: In database of paper of international biology medicine, the paper that concerns with flu has nearly 50000, and the paper that concerns with common cold is less than 4000.
On the history, flu craze every other 10 ～ appear 50 years. Be apart from now last time flu craze has had 40 years, a lot of experts worry about new flu craze extremely urgent. The 3 flu craze of last centuries is discovered those who cause to be the new-style flu virus that evolve by avian flu virus and comes, so avian flu is in caused very great attention in recent years. But avian flu virus becomes directly can be in the crowd the possibility of retailer flu virus is not large, it is easy to if have the pig does intermediary to be met,think normally much -- the swine flu that you understood why to appear this to be able to travel in the crowd now lets a whole world be like face archenemy.
A lot of person first time hear the pig still can have flu, because this generated fear to pork, some countries are returned begin in order to prevent a pig for flu large-scale kill a hog or prohibit importing pork. Did not discover this kind of virus between the pig at present, somebody -- the public figure that raises pig employment especially -- for the pig querulous, think the pig was treated unjustly. Take on to do not want to let a pig notoriety, after World Health Organization was calling a pig flu, the name is A H1N1 flu, home it Chinese flu of melt into armour H1N1, media sometimes flat abbreviation is armour flu. This kind of abbreviation is very undeserved. Flu virus cent is armour, second, third (or A, B, C) 3 model, among them the commonnest is armour model, annual and popular seasonal flu is armour flu mostly. Call this special flu simply accordingly armour flu can not distinguish it and general flu.
Put in two kinds of protein in the surface of flu virus. A kind of red blood cell that can make blood medium is condensed together, be called blood to coagulate so element (abbreviation HA or H) . Another kind of protein can nerve ammonia acid (element of a kind of saccharide) decompose,[link widoczny dla zalogowanych] ,, call nerve ammonia acid so enzymatic (abbreviation NA or N) . Because these two kinds of protein are exposed in flu virus outside,[link widoczny dla zalogowanych] ,, after flu virus enters human body, they became the target of system of human body immunity. If these two kinds of protein appeared to mutate, immune system cannot identify them, flu virus can be escaped. Because this virus learns the home to do farther classification with respect to the mutation circumstance according to these two kinds of protein, make up on different number. This flu is armour H1N1 inferior model, those two numbers state its blood coagulates respectively the type with element and nerve ammonia enzymatic acid. This inferior model flu virus is not new discovery, bring about 1918 ～ 1919 the virus of flu craze also is armour H1N1 inferior model. It is the commonnest flu virus actually inferior model, seasonal 2006 it causes flu has an in part about. The flu this calls armour H1N1 flu, cannot make clear its characteristic likewise.
Because this a few virus learn the home not to make allowances for World Health Organization and each country government to try to protect the pains of the course of study that raise a pig, still insist to call this flu swine flu. Although did not discover it once travelled in swinery at present, also show without direct evidence it sends a person from the pig, but indirect evidence makes clear it can be to come from a pig only. Flu virus always shares 8 gene part. This flu virus has 6 gene extract is swine flu virus, 2 part that remain belong to person flu virus and avian flu virus respectively so, but had been gone to early by union 1998 inside swine flu virus.
Why can the gene segment of person flu virus and avian flu virus running to swine flu went inside virus? Flu virus is passed and apparently union accepting put oneself in another's position just can infect the cell cell. On person cell and avian cell accept put oneself in another's position not identical, person flu virus and avian flu virus are mixed only respectively the union accepting put oneself in another's position that answers relatively, accordingly person flu virus cannot be affected normally avian, avian flu virus also cannot affect a person normally. But the cell in the pig apparently at the same time existence accepts put oneself in another's position two kinds this, besides swine flu virus, person flu virus and avian flu virus also can affect a pig. Such, if a pig is affected to go up by these 3 kinds of virus at the same time, they undertake possibly inside the cell of the pig " cross " , the brand-new flu virus of the gene part that constitutes a kind to contain pig, person and avian flu virus at the same time, then reinfection gives person or bird.
Should have such " cross " , the pig must have an opportunity to have intimate contact with birds, person at the same time. Be in Asian south rural area, pig, chicken, duck, goose often is raised together, and get along with master a very short time, the cross that is flu virus offerred auspicious opportunity. So Asian south is considered as the birthplace of new flu virus normally. Somebody was written on the newspaper recently civil regard contemporary hoggery as virus develops base, ascribe the occurrence of new-style flu virus to modern breed aquatics environment, it is the pig is in tenacious ground to disband the desire that come home to human expression (" the metaphor of the pig " , " Beijing youth signs up for " on May 10,[link widoczny dla zalogowanych] ,, 2009) . This is bookman assume sth as a matter of course purely is lyric. Person and rasorial cattle " harmonious coexist " means of tradition breed aquatics, just be the breeding ground that fosters new-style virus. powered by:[link widoczny dla zalogowanych]
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